Publications:
Journals
(undergraduate
co-authors in red)
Smith M. A.,
Chisholm K. A., Bryant P. A., Greene J. L., McClean J. M., Stoops W.
W. & Yancey D. L. (2004). )
Social and environmental influences on sensitivity to mu opioid in
rats: Importance of an opioid’s relative efficacy at the mu
receptor. Psychopharmacology [Epub ahead of print: DOI:
10.1007/s00213-005-2218-2].
Morgan D., Smith M. A. & Roberts D. C. S. (2005) Binge
self-administration and deprivation produces sensitization to the
reinforcing effects of cocaine in rats. Psychopharmacology, 178,
309-316.
Smith M. A., Craig C. K. &
French A. M. (2004). Agonist and antagonist effects of
benzodiazepines on motor performance: Influence of relative
intrinsic efficacy and task difficulty. Behavioural Pharmacology,
15, 215-223.
Smith M. A., Yancey
D. L., Morgan D., Liu Y., Froestl W., & Roberts D. C. S.
(2004). Effects of positive allosteric modulators of the GABAB
receptor on cocaine self-administration. Psychopharmacology, 173,
105-111.
Smith
M. A., McClean J. M. &
Bryant P. A. (2004). Sensitivity to the effects of a kappa
opioid in rats with free access to exercise wheels: Differential
effects across behavioral measures.
Pharmacology, Biochemistry and Behavior, 77, 49-57.
Smith
M. A., McClean J. M. &
Greene J. L. (2003). Enhanced sensitivity to the
antinociceptive effects of kappa opioids in naltrexone-treated rats:
Dose and time-dependent effects. Behavioural Pharmacology, 14,
641-647.
Smith
M. A., Bryant P. A. &
McClean J. M. (2003). Environmental enrichment enhances
sensitivity to the effects of kappa opioids: Studies on
antinociception, diuresis and conditioned place preference.
Pharmacology, Biochemistry and Behavior, 76, 93-101.
Smith
M. A. & Yancey D. L. (2003).
Sensitivity to the effects of opioids in rats with free access to
exercise wheels: Mu opioid tolerance and physical dependence. Psychopharmacology,
167, 426-434.
Smith
M. A., Gordon K. A., Craig C. K., Bryant P.
A., Ferguson M. E., French A. M., Gray J. D., McClean J. M. &
Tetirick J. C. (2003). Interactions between opioids and
cocaine on locomotor activity: Influence of an opioid’s relative
efficacy at the mu receptor. Psychopharmacology, 167,
265-273.
Smith,
M. A. & French, A. M. (2002).
Age-related differences in sensitivity to the antinociceptive
effects of kappa opioids in adult male rats. Psychopharmacology, 166,
255-264.
Smith, M. A. & Gray, J. D. (2001).
Age-related differences in sensitivity to the antinociceptive
effects of opioids in male rats: Influence of nociceptive intensity
and intrinsic efficacy at the mu receptor. Psychopharmacology, 156,
445-453.
Smith, M. A. & Stoops, W. W.
(2001). Sensitivity to the effects of sedative-hypnotics on motor
performance: Influence of task difficulty and chronic phenobarbital
administration. Behavioural
Pharmacology, 12, 125-134.
Smith, M. A., Barrett, A. C. &
Picker, M. J. (1999). Antinociceptive effects of opioids following
acute and chronic administration of butorphanol: Influence of
stimulus intensity and relative efficacy at the mu receptor. Psychopharmacology, 143,
261-269.
Morgan, D., Cook, C. D., Smith, M. A. & Picker, M. J. (1999).
Interaction between the antinociceptive effects of partial opioid
agonists and morphine: Influence of nociceptive stimulus
intensity. Anesthesia
and Analgesia, 88, 407-413.
Smith, M. A. & Picker, M. J. (1998). Tolerance and cross
tolerance to the rate-suppressing effects of opioids in butorphanol-treated
rats: Influence of maintenance dose and relative efficacy at the mu
receptor. Psychopharmacology, 140, 57-68.
Smith, M. A., Pitts, R. A. & Picker, M. J. (1997). Tolerance and
cross tolerance to the accuracy- and rate-decreasing effects of mu
opioids in rats responding under a fixed-consecutive-number
schedule. Drug and Alcohol Dependence, 46, 19-30.
Picker, M. J., Benyas, S., Horowitz, J. A.,
Thompson, K., Mathewson, C. & Smith, M. A. (1997).
Discriminative stimulus effects of butorphanol: Influence of
training dose on the substitution patterns produced by mu, kappa and
delta opioids. Journal
of Pharmacology and Experimental Therapeutics, 279,
1130-1141.
Smith, M. A. & Picker, M. J. (1995). Examination of the kappa
agonist and antagonist properties of opioids in the rat drug
discrimination procedure: Influence of training dose and intrinsic
efficacy. Behavioural Pharmacology, 6, 703-717.
Picker, M. J., Smith, M. A. & Morgan, D. (1994). Assessment of
the relative intrinsic efficacy of profadol and meperidine in a
pigeon drug discrimination procedure: Relevance to partial
substitution patterns. Behavioural Pharmacology, 5, 61-70.
Picker, M. J., Yarbrough, J., Hughes, C. E., Smith, M. A., Morgan,
D. & Dykstra, L. A. (1993). Agonist and antagonist effects of
intermediate efficacy mu opioids in the pigeon drug discrimination
procedure: Influence of training dose and individual responsiveness. Journal of Pharmacology and Experimental Therapeutics, 266,
756-767.
Published
Abstracts & Presentations
(undergraduate
co-authors in red)
Smith M. A. &
Lyle M. A. (2005) Chronic exercise
decreases sensitivity to mu opioids in female rats: Correlation with
exercise output. (presented at the 67th annual meeting
of the College on Problems of Drug Dependence in Orlando, FL)
Smith
M. A. & Roberts D. C. S. (2004). Lesions of the dorsal
prefrontal cortex block cocaine sensitization. (presented
at the 112th annual meeting of the American Psychological
Association in Honolulu, HI)
Smith
M. A. & Greene J. L. (2004).
Cross sensitization between opioids and cocaine. (presented
at the 66th annual meeting of the College on Problems of
Drug Dependence in San Juan, PR)
Smith
M. A., Bryant P. A. & McClean
J. M. (2003). Environmental enrichment enhances sensitivity
to kappa opioids. (presented
at the 65th annual meeting of the College on Problems of
Drug Dependence in Bal Harbour, FL)
Morgan D., Mateo Y., Collins A. J., Yancey D. L., Childers S. R.,
McCracken C., Smith M. A., Jones S. R. & Roberts D. C. S. (2003). Neurobiological alterations associated with
changes in the reinforcing efficacy of cocaine. (presented at the 65th annual meeting of the College on
Problems of Drug Dependence
in Bal Harbour, FL)
Smith
M. A., Yancey D. L., Morgan D., Liu Y., Froestl W. & Roberts D.
C. S. (2003). Positive allosteric modulators of the GABAB
receptor decrease cocaine self-administration.
Society for Neuroscience Abstracts, 29, 424.16. (presented
at the 33rd annual meeting of the Society for
Neuroscience in New Orleans, LA)
Smith M. A. & McClean
J. M. (2002). Chronic naltrexone treatment enhances
sensitivity to the antinociceptive effects of kappa opioids. Society
for Neuroscience Abstracts, 28, 783.8.
(presented at the 32nd
annual meeting of the Society for Neuroscience in Orlando, FL)
Smith M. A.,
Gordon K. A., Craig C. K., Ferguson M. E.,
French A. M., Gray J. K. & McClean
J. M. (2002). Drug
interactions between cocaine and mixed-action opioids on locomotor
activity. Drug
and Alcohol Dependence, 66 Suppl 1, 166. (presented
at the 64th annual meeting of College on the Problems of
Drug Dependence in Quebec City, Quebec)
Smith M. A. & Yancey
D. L. (2001). Chronic exercise increases nociceptive
threshold but reduces sensitivity to the effects of mu opioids. Society
for Neuroscience Abstracts, 27, 960.14. (presented at the 31st annual meeting of the Society for
Neuroscience in San Diego, CA)
Smith M. A. & French
A. M. (2001). Young and aged rats differ in sensitivity to
the antinociceptive effects of kappa opioids.
Drug and Alcohol Dependence, 63 Suppl 1, 148. (presented
at the 63rd annual meeting of the College on Problems of
Drug Dependence in Scottsdale, AZ)
Smith M. A., Chisholm
K. A., Stoops W. W. & Lawson V. C. (2000). Environmental
enrichment enhances sensitivity to the antinociceptive effects of mu
opioids. Society for Neuroscience Abstracts, 26, 282. (presented
at the 30th annual meeting of the Society for
Neuroscience in New Orleans, LA)
Smith M. A., Stoops
W. W. & Morgan D. (2000). Sensitivity to the effects of
CNS depressants on motor performance in phenobarbital-treated rats. Drug
and Alcohol Dependence, 60 Suppl 1, 207. (presented
at the 62nd annual meeting of the College on Problems of
Drug Dependence in San Juan, PR)
Smith M. A. & Gray
J. D. (1999). Young and aged rats differ in sensitivity to
the antinociceptive effects of mu opioids. Behavioral
Pharmacology, 10 Suppl 1. (presented
at the 43rd annual meeting of the Behavioral Pharmacology
Society in Boston, MA)
Smith M. A., Barrett
A. C. & Picker M. J. (1998). Tolerance to the
antinociceptive effects of mu opioids in butorphanol-treated rats. NIDA
Research Monograph, 179, 231. (presented
at the 60th annual meeting of the College on Problems of
Drug Dependence in Scottsdale, AZ)
Smith
M. A., Walker E. A. & Picker M. J. (1997). Changes in potency of
mu and kappa opioids following chronic administration of butorphanol.
Society for Neuroscience Abstracts, 23, 986. (presented
at the 27th annual meeting of the Society for
Neuroscience in New Orleans, LA)
Smith
M. A. & Picker M. J. (1997). Discriminative stimulus properties
of the partial mu agonist dezocine. NIDA Research Monograph, 178,
169. (presented at the 59th
annual meeting of the College on Problems of Drug Dependence in San
Juan, PR)
Picker
M. J., Cook C. D., Morgan D. & Smith M. A. (1997). Drug
discrimination in pigeons successively trained to discriminate the
mu opioid butorphanol and the kappa opioid bremazocine. NIDA
Research Monograph, 178, 169. (presented
at the 59th annual meeting of the College on Problems of
Drug Dependence in San Juan, PR)
Smith M. A. & Picker M. J. (1996). Development of tolerance and
cross tolerance to the effects of opioids in butorphanol-treated
rats. NIDA Research Monograph, 174, 168. (presented
at the 58th annual meeting of the College on Problems of
Drug Dependence in Nashville, TN)
Morgan D., Smith M. A., Cook C. D. & Picker M. J. (1996).
Effects of levorphanol, buprenorphine and butorphanol alone and in
combination with morphine in a rat tail withdrawal procedure. NIDA
Research Monograph, 174, 161. (presented at the 58th annual meeting of the College on
Problems of Drug Dependence in Nashville, TN)
Smith M. A., Benyas S., Thompson K.,
Horowitz J. A. & Picker M. J. (1995). Discriminative
stimulus effects of butorphanol: Involvement of mu, kappa and delta
opioid receptor activity. NIDA Research Monograph, 162, 339.
(presented at the 57th
annual meeting of the College on Problems of Drug Dependence in
Scottsdale, AZ)
Smith M. A., Pitts R. C., Dykstra L. A. & Picker M. J. (1994).
Effects of opioids with varying degrees of intrinsic efficacy at the
mu receptor on fixed-consecutive number responding in rats. Society
for Neuroscience Abstracts, 20, 227. (presented
at the 24th annual meeting of the Society for
Neuroscience in Miami Beach, FL)
Smith M. A. &
Picker M. J. (1994). Characterization of the discriminative stimulus
effects of kappa opioids and mixed action opioids: Role of training
dose and intrinsic efficacy. NIDA Research Monograph, 153,
92. (presented at the 56th annual meeting of the College on
Problems of Drug Dependence in West Palm Beach, FL)
Smith M. A., Morgan D., Hughes C. E., Dykstra L. A. & Picker M.
J. (1993). Stimulus effects of mixed action opioids: Interactions of
training dose, intrinsic efficacy and inter-animal differences. NIDA
Research Monograph, 141, 276. (presented
at the 55th annual meeting of the College on Problems of
Drug Dependence in Toronto, Ontario)
Morgan D., Smith M. A. & Picker M. J. (1993). Stimulus effects
of profadol and meperidine: Interaction with fentanyl and
butorphanol. NIDA Research Monograph, 141, 275. (presented
at the 55th annual meeting of the College on Problems of
Drug Dependence in Toronto, Ontario)
